Antiretroviral Agents Effectively Block HIV Replication after Cell-to-Cell Transfer
نویسندگان
چکیده
منابع مشابه
Antiretroviral agents effectively block HIV replication after cell-to-cell transfer.
Cell-to-cell transmission of HIV has been proposed as a mechanism contributing to virus escape to the action of antiretrovirals and a mode of HIV persistence during antiretroviral therapy. Here, cocultures of infected HIV-1 cells with primary CD4(+) T cells or lymphoid cells were used to evaluate virus transmission and the effect of known antiretrovirals. Transfer of HIV antigen from infected t...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2012
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.01044-12